166 research outputs found

    The problem with environmental security: challenging the either/or approach of national versus human security in the context of the Mekong River Basin

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    One of the most important ideas to emerge from security studies in the past forty years is the field of research known as ‘environmental security studies’ (ESS). It has not, however, had the impact on security studies in general that it might have expected to – given the growing concerns regarding the scale and pace of environmental changes in the 20th and 21st centuries. This thesis therefore firstly seeks to understand the nature of ESS, asking whether ESS has a central theoretical core that enables it to analyse the links between the environment and security. The research shows that the ESS literature does not have a central tenet, nor a united epistemological or methodological approach. The second area of research therefore asks if there is a common theme that can be discerned within the literature. Research indicates that there is a way of understanding ESS in a more coherent fashion in that the majority of ESS scholars endeavour to comprehend the systemic security impact of environmental processes. The problem is that there is no analytical bridge between the environment, the state and the individual. This thesis therefore forwards a unique approach that argues that rather than the current either state-centric or a human security approach to ESS, it must be understood as a combination of both. This approach is termed “Systemic Environmental Security” (SES). SES is an analytical framework that takes into account the way that environmental processes give rise to both state security and human security concerns simultaneously. The thesis finally explores the unique insights provided by SES. This is achieved through a relevant case study of the Mekong River Basin. It is hoped that these unique insights provided by Systemic Environmental Security can be applied in a range of contexts, providing clearer conceptualisations of the complex relationship between security and the environment

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    Regular use of beta2-agonists might result in increased bronchial hyper-responsiveness (BHR) and decreased forced expiratory volume in 1 sec (FEV1). It has been suggested that these possible detrimental effects are not a real deterioration of the disease, but that it might be only a transient (rebound) effect shortly after discontinuing this regular use. Moreover, these effects are thought to occur especially during short-acting and not during long-acting beta2-agonists use. The aim of this study was to invest gate whether a rebound effect (a pharmacological deterioration effect diminishing after several hours) in FEV1 and PC20 (concentration of histamine causing a 20% fall in FEV1 with regard to baseline) occurred after cessation of regular use of beta2-agonists, and whether this occurred both after short-acting and long-acting beta2-agonists. Allergic asthmatic patients (n = 134) were randomly allocated to the use of a short-acting (salbutamol), a long-acting beta2-agonist (formoterol) or placebo for 12 weeks (double-blind, double-dummy). No other asthma medication was allowed, including inhaled corticosteroids. At the start and every 4 weeks later FEV and PC20 were measured, each time at least 12 h after the last doses of study medication, which is in the possible rebound period. To investigate whether a (transient) rebound effect occurred, parameters were additionally measured at least 72 h later after discontinuation of the study medication. After 12 weeks of short-acting beta2-agonist use, a drop was seen in FEV1 from 85.6 (+/- 2.21)% predicted to 78.8 (+/- 2.9)% predicted, measured 15 h (median) after the last doses of medication. This was significantly different compared to placebo. When measured 168 h (median) later FEV1 recovered to 85.5 (+/- 2.4)% predicted, comparable to baseline. PC20 decreased with -1.17 (+/- 0.44) doubling dose after 12 weeks of short-acting beta2-agonist use, measured 15 h after the last doses of medication, which was significantly different compared to placebo. However, 168 h later PC20 recovered slightly with +0.55 (+/- 0.34) doubling dose, but this value was still lower compared to placebo. In contrast, during long-acting beta2-agonist and placebo use no significant changes were seen. In conclusion, the use of short-acting beta2-agonists resulted in a transient (rebound) effect in FEV while the effects on PC20 may point to a real deterioration of the disease. Long-acting beta2-agonist and placebo use showed no changes.We conclude that a mono-therapy of short-acting and not of long-acting beta2-agonists might have deleterious effects in asthma

    Animation in relational information visualization

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    In order to be able to navigate in the world without memorizing each detail, the human brain builds a mental map of its environment. The mental map is a distorted and abstracted representation of the real environment. Unimportant areas tend to be collapsed to a single entity while important landmarks are overemphasized. When working with visualizations of data we build a mental map of the data which is closely linked to the particular visualization. If the visualization changes significantly due to changes in the data or the way it is presented we loose the mental map and have to rebuild it from scratch. The purpose of the research underlying this thesis was to investigate and devise methods to create smooth transformations between visualizations of relational data which help users in maintaining or quickly updating their mental map

    Identity and Interests: Understanding the Meltdown in Israeli-Turkish Relations 2002-2012

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    The recent deterioration of the strong bilateral alliance between Israel and Turkey has significant affects on the balance of power within the Middle East. As such, it is important that scholars determine why this meltdown has occurred. This thesis sought to explain the deterioration of relations between Israel and Turkey and overcome gaps in the existing literature concerned with this meltdown of bilateral relations by taking a fresh look into the role of identity and the interests it creates. Hence, the framework of Wendtian constructivism was applied in order to examine the social origins and impacts of identity and interests on alliance formation and deterioration. In this thesis, I suggested that Israel’s identity has changed slowly over the past decade and as such, should be perceived as ‘relatively’ stable. Conversely, however, Turkey’s national identity changed sharply, drifting away from the Ataturk agenda of Westernisation and secularism towards an Islamic heritage. In order to strengthen my argument that this shift in Turkish identity has primarily accounted for the deterioration of its relations with Israel, I analysed Turkish attitudes towards foreign policies other than its bilateral relationship with Israel, as well as its newly defined interests. Thus, whereas Israel’s relatively stable national identity and domestic policies were matched by its relatively stable foreign interests over the past decade, deep changes to Turkey’s national identity redirected its domestic policies under Recep Tayyip Erdoğan’s government. Consequently, Turkey has employed a number of political tensions and events as pretexts in order to unilaterally disengage from its relations with Israel so that it can further new foreign policies and interests. Identity matters, and for better or worse, identity changes precede foreign policy change, a lesson we must not forget

    Supplemental oxygen for COPD-patients with nocturnal desaturations?

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    COPD : longfunctie in de eerstelijn

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    Contains fulltext : 20584___.PDF (publisher's version ) (Open Access

    Control of breathing in health and disease.

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    Contains fulltext : 49123.pdf (publisher's version ) (Closed access

    Control of breathing in health and disease.

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